Best Glycine for Sleep (2026): The Two Real Glycine Capsules, and the Glycinate Blends People Confuse With Them

One amino acid, one number. Life Extension Glycine 1000 mg states 1000 mg per capsule and 100 capsules, and describes the product as sleep support, which is the label's phrase and the only one we repeat. $12.00 / 100 = $0.12 per capsule; the serving size on the panel decides how many capsules make a serving.

Life Extension's melatonin products, including the 300 mcg capsule ($7.50) that leads best low-dose melatonin, are reviewed in the Life Extension melatonin review. Glycine's place among the melatonin-free options is in best melatonin-free sleep aids.

Three hundred capsules of the same number. Double Wood Glycine 1000 mg states 1000 mg per capsule and 300 capsules, and calls itself a relaxing amino acid supplement for sleep support, the label's language. $19.95 / 300 = about $0.067 per capsule.

Double Wood's other single-ingredient sleep capsules share the same labeling habit: Apigenin 50 mg, 120 capsules ($24.85) and GABA 1,000 mg, 150 capsules ($14.95), each ranked on its own page (best apigenin supplements for the first). The magnesium glycinate from the same brand is below, labeled as the magnesium product it is.

Glycine in a formula, named as itself. Nello Supersleep is a nighttime drink mix whose title names ashwagandha, Maizinol (a branded corn-leaf extract), L-glycine and magnesium glycinate. That makes it the only blend in our catalog that names glycine as a distinct ingredient rather than as half of the word "glycinate." Servings and per-serving amounts are on the panel; melatonin is not named.

Nello's daytime sibling, Supercalm ($39.95), names L-theanine and KSM-66 ashwagandha and is not a sleep product. The drink-mix category as a whole, with and without melatonin, is ranked in best magnesium sleep powders and best sleep powders.

The most common way people end up taking glycine without meaning to. Double Wood Magnesium Glycinate 400 mg states its magnesium glycinate amount and its 180 count. Glycinate is magnesium chelated to glycine, so every capsule contains some glycine, but the title, like every glycinate title on Amazon, does not say how much, and the product is labeled and sold as magnesium.

Double Wood sells both, which is convenient for someone who wants to try glycine and magnesium separately before combining them: the Glycine 1000 mg above and this capsule together come to $36.94 for 480 capsules. The ingredient comparison is melatonin vs magnesium.

Glycinate plus melatonin, from the fast-dissolve brand. Natrol Sleep and Restore Capsules name magnesium glycinate and GABA and state 5 mg melatonin, describing the product as a calm magnesium sleep aid in the label's words. No count, no magnesium figure, no glycine figure.

Natrol's whole range, from the 1 mg fast-dissolve to this blend, is in the Natrol melatonin review; the blends that pair magnesium and melatonin are ranked by melatonin figure in best melatonin with magnesium. The melatonin caution applies: adults only, do not drive after taking it, and consult a doctor if pregnant or nursing.

A well-known blend, with the magnesium form spelled out. Nested Naturals Luna Sleep Aid and Magnesium Glycinate Chelate states 180 capsules and names the chelate; the rest of the formula, and whether melatonin is in it, is on the panel. "Chelate" is the chemistry word for magnesium bound to glycine, which is the same thing "glycinate" means.

The Luna family, including the stated-Melatonin-Free version that holds a slot in best melatonin-free sleep aids, is reviewed in the Nested Naturals Luna review.

The advertised one. Relaxium Sleep states 5 mg melatonin, names magnesium glycinate and states a 30-day supply, which is more numerical disclosure than most blends: $27.90 / 30 = $0.93 per night. The magnesium amount and any glycine figure are not in the title.

Relaxium is compared with the rest of the magnesium-melatonin shelf in best melatonin with magnesium. As with every melatonin product: adults only, do not drive after taking it, consult a doctor if pregnant or nursing, and ask a pharmacist about interactions with blood thinners and blood-pressure or diabetes medication.